What New in Overactive Bladder?-Whats new in overreactive bladder.mp4 (1080p HD)

Video Transcription

Video Summary

Dr. Sarah Jenny, a urogynecologist at the University of New Mexico, presents an overview of overactive bladder (OAB) and urgency urinary incontinence (UUI), highlighting its significant impact on patients' quality of life. She explains the bladder's normal function and how spasms and nerve hypersensitivity cause UUI. Treatment progresses from behavioral therapies (like bladder training and lifestyle changes) to oral medications (anticholinergics with dementia risks and newer beta-3 agonists) and third-line options such as Botox injections and neuromodulation. Dr. Jenny introduces a PCORI-funded, multi-center randomized study comparing beta-3 agonist medications to bladder Botox for women with refractory UUI. The trial aims to improve treatment accessibility and reduce barriers through community outreach and participant incentives. Recruitment is ongoing across multiple U.S. sites, including New Mexico, through 2027. Contact details and participation information for the study are provided to encourage patient enrollment and collaboration with local providers.

Keywords

overactive bladder

urgency urinary incontinence

beta-3 agonists

Botox injections

PCORI-funded study